Well, the development of some of the drugs for chemical immobilization in the zoo field started in the 1950s. I didn’t graduate from veterinary school until ’55. And so, as I said with the chimpanzee, the only anesthetic agent that I had was a phenobarbital, which was a human sedative. We had other drugs that were used, drug called succinylcholine, which is a muscle paralyzer, and I used that on horses. So I knew about that, and the tranquilizers cable on the scene, I knew how to use tranquilizers. So we started to use those in wild animals, and they have limited use, at least most of the tranquilizers do. But the development of the powerful opioids, the narcotics, if you will, came on board about the time that I entered the zoo field intensely. So that my first experiences with these were with things like nicotine.